Figures For Lactate Correlation Manuscript

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Lactate levels in DCD livers during perfusion

Figure 1: Plot of lactate levels in individual livers during NMP

Transcriptome correlation analysis im DCD livers

Figure 2: Heatmap of all positively correlating genes

Figure 3: Heatmap of all negatively correlating genes

Figure 4: Plot of all positively correlating genes

Figure 5: Plot of all negatively correlating genes

Figure 6: Dot-plot of enriched GOterms in correlating genes.

Figure 1: Lactate levels in DCD livers during perfusion.

Lactate levels were measured in the perfusate at multiple times throughout the NMP process.

Figure 1: Lactate levels measured in 10 DCD livers during perfusion. After perfusion, each liver was determined to have high (blue), intermediate (yellow) or low (red) performance based off of their lactate levels at 3 hours of perfusion (dashed box).

Transcriptome correlation analysis im DCD livers

Correlation of gene expression from the transcriptomic analysis of pre-perfusion livers with lactate levels at 3 hours of perfusion.

Figure 2: Heatmap of all genes found to have expression levels in an RNAseq analysis that positively correlate with 3 hour NMP lactate levels in 10 DCD livers.

Figure 3: Heatmap of all genes found to have expression levels in an RNAseq analysis that negatively correlate with 3 hour NMP lactate levels in 10 DCD livers.

Figure 4: Standardized and mean standardized gene expression data for positively correlating genes compared to the lactate levels.

Figure 5: Standardized and mean standardized gene expression data for negatively correlating genes compared to the lactate levels.

Figure 6: GOterm dotplot.